As Winston Churchill once quipped, “God so loved the world that he did not send a committee.”
The Drafting Committee of the Review Conference on the Treaty on the Non-Proliferation of Nuclear Weapons (NPT) was unable to draft an outcome document. Even with last-minute efforts of the Conference President and the UN Disarmament Secretariat to smooth over all controversial wording in the document, there was no consensus. In the end, the US, the UK, and Canada refused to accept the final document citing the proposal of a nuclear-weapon free zone in the Middle East.
Since there has been no visible progress on reducing nuclear weapons through negotiations among the nuclear-weapon States--the US and Russia hold some 95% of weapons--efforts have been made to make legally-binding nuclear-free zones.
The first nuclear-free zone to be negotiated was a direct aftermath of the Cuban Missile Crisis in 1962. A nuclear exchange between the US and the USSR was close enough that Latin American leaders were moved to action. Mexico immediately began to call for a de-nuclearization of Latin America. In February 1967, the Treaty for the Prohibition of Nuclear Weapons in Latin America was signed. It established a permanent and effective system of control containing several pioneering elements, as well as a body to supervise the Treaty.